Understanding Ketamine Treatment

 Initially developed in the 1960s as a powerful anesthetic, ketamine has recently gained recognition as an innovative therapy for various mental health challenges, most notably major depression and suicidal thoughts. Its clinical use has since broadened to include conditions like OCD (obsessive-compulsive disorder), PTSD, postpartum depression, and bipolar disorder.

At Phoenix Mental Health, we provide comprehensive ketamine treatment options, including IV (intravenous), IM (intramuscular), and intranasal (inhaled) administration—all delivered safely under the guidance of trained medical professionals.

How Does Ketamine Therapy Work?

Ketamine operates by inhibiting NMDA receptors in the brain, resulting in elevated levels of glutamate, a critical neurotransmitter. This action stimulates AMPA receptors, which are thought to play a key role in rapid mood elevation. Unlike conventional antidepressants that primarily influence serotonin, dopamine, or norepinephrine, ketamine directly impacts glutamate pathways.

This distinct mechanism is what sets ketamine apart, offering new possibilities for individuals who haven’t benefited from standard treatments.

What to Expect During a Ketamine Session

Each ketamine session is a personalized experience. Effects may vary from person to person, and even from one session to the next. Common experiences include a sense of dissociation, changes in time perception, enhanced color visuals, and deep emotional calm or connection. These sensations are temporary and usually wear off shortly after treatment concludes.

What to Expect During a Ketamine Session

Duration of Ketamine’s Effects

IV and IM ketamine therapies generally provide longer-lasting relief than the intranasal option (Spravato). Treatment typically starts with two sessions weekly over four weeks, followed by a maintenance plan tailored to the patient’s response, with booster treatments spaced out over time.
Spravato treatments begin with twice-weekly dosing during the first month, then transition to weekly sessions in the second month. From the third month onward, the schedule is customized based on your individual needs in collaboration with your provider.

Duration of Ketamine’s Effects

Is Ketamine Right for You?

If you are 18 or older and haven’t found sufficient relief from at least one antidepressant, ketamine therapy may be a suitable alternative.

Is Ketamine treatment right for you?

Will somebody be with me during treatment?

Absolutely. For IV and IM treatments, a licensed medical professional will administer and monitor your session to ensure your safety. Afterward, you’ll spend time in a calm recovery setting where you can relax, read, or listen to music until you’re ready to leave.

Spravato sessions require less intensive monitoring. Initially, a doctor will be present; after stabilization, a certified Spravato technician will oversee your treatments, with a physician always on-site.

Will somebody be with me during treatment?
Ketamine Treatment Options & Costs in San Antonio

Spravato (Nasal Ketamine)

IV (intravenous) Ketamine treatment

IM (intramuscular) Ketamine treatment

Feel free to contact our office with any questions.

Payment Options for Ketamine Treatment

Phoenix Mental Health - Private Pay Option

Our private pay program emphasizes personalized, responsive care without the limitations of insurance. This approach allows for greater scheduling flexibility, more focused attention, and a treatment plan built entirely around your needs. We’re happy to provide more information and pricing if this option aligns with your preferences.

Insurance-Covered Care

We accept most major insurance plans, including Medicare, particularly for medication management services. We understand that private pay may not be viable for everyone, but we believe in making high-quality care accessible. Insurance-covered visits may vary in duration and availability due to provider network restrictions.

Phoenix MH Concierge
Phoenix MH Insured Care
Clinic Location
Leon Springs / Dominion Area of San Antonio
Medical Center of San Antonio
Payment Method
Private Pay
Commercial Insurance, Medicare
Wait Time for Initial Appt.
1-2 Weeks
2-4 Weeks
Average Time of Appointments
30 Minutes
10-15 Minutes
Customized Treatment Plans
Tailored to Your Needs
Tailored to Your Needs
Autonomy and Involvement in Clinical Decision Making
Active Participation From Patients In Any & All Treatment Decisions
Active Participation From Patients In Any & All Treatment Decisions
Response from Providers to Patient Inquiries
Less That 24 Business Hours
24-72 Business Hours
Types of Appointments Offered
In-Person, Phone, Virtual
In-Person Only

Discover Peace at Our Clinic

Contact us today to discover how ketamine treatment can offer renewed hope and a path to overcoming depression.

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    New Location in the San Antonio Medical Center Now Accepting Insurance for Medication Management & Spravato Treatment.

    New Location in the San Antonio Medical Center Now Accepting Insurance for Medication Management & Spravato Treatment.